This chapter, by Sarah B. Boesdorfer, discusses how firsthand experience learning chemistry content, while engaged in science and engineering practices or crosscutting concepts, helps preservice teachers experience the type of instruction they will eventually be expected to provide. Examples of such lessons in postsecondary chemistry instruction are offered. Teacher background information, standards, assessments, references, and resources are provided. This book selection also includes the Table of Contents, Foreword, Preface, Acknowledgments, and Index.