In this unit, students will isolate DNA suitable for sequencing and other analyses. Students use bioinformatics software to find differences between normal and mutant DNA sequences, then use DNA restriction mapping to confirm the differences. In order to perform lab procedures in a reasonable time, students will work with bacterial rather than human DNA. The methods and thinking process are much the same as for characterizing genes linked to human disease.
Type Book ChapterPub Date 3/1/2009Stock # PB232X_3u