Written for K–12 educators, this e-book brings together contemporary approaches in science, STEM, and language education, with a specific focus on multilingual learners. Incorporating learnings from studies like A Framework for K–12 Science Education, Next Generation Science Standards, and English Learners in STEM Subjects, it aims to connect research, policy, and practice to enhance curriculum development, teaching strategies, and professional learning for educators. Its approach to professional learning provides conceptual grounding for teachers to understand the “when” and “why” of classroom strategies, thus giving them agency in their instructional decision-making.