Sponsoring Company: 3D Molecular Designs

Explore the processes of DNA replication, transcription, and translation using manipulatives that support the NGSS three dimensions, most notably the SEP of developing and using models.

TAKEAWAYS:
1. Model the leading and lagging strands of DNA; 2. Understand the semiconservative nature of DNA replication; and 3. Investigate how a change in DNA code can result in a change in the protein produced.

SPEAKERS:
Susan Auld (Sehome High School: Bellingham, WA)

Sponsoring Company: Bio-Rad Laboratories

In this hands-on walk-through, learn about a CRISPR gene editing classroom activity and discuss strategies to reveal student misconceptions with a free paper model set.

TAKEAWAYS:
1. Free paper models for teaching CRISPR gene editing and revealing student misconceptions; 2. A deeper understanding of CRISPR gene editing at the molecular level; and 3. Information about a CRISPR gene editing classroom activity.

SPEAKERS:
Damon Tighe (Bio-Rad Laboratories: Hercules, CA)

Sponsoring Company: 3D Molecular Designs

Mitosis, meiosis, chromosome structure, and crossing over will be explored in this hands-on modeling event. Bring your student hat and be ready to engage.

TAKEAWAYS:
1. Model chromosome structure and anatomy; 2. Compare and contrast mitosis and meiosis; and 3. Model mechanisms that contribute to genetic variation.

SPEAKERS:
Christina Bowers (Meridian School: Round Rock, TX)

Sponsoring Company: 3D Molecular Designs

Work through cycles of PCR using foam manipulatives that make the invisible visible. Demonstrate the role of Taq polymerase, primers, and nucleotides as they copy target DNA.

TAKEAWAYS:
1. Explore the chemical mechanism involved in PCR; 2. Model polymerase chain reaction and how flanking primers result in the exponential amplification of a short product; and 3. Use a real-world scientific example of how PCR is used to help solve a crime.

SPEAKERS:
Susan Auld (Sehome High School: Bellingham, WA)

Sponsoring Company: Beyond Labz

Built on a platform developed over 20 years, Beyond Labz creates an open-ended environment providing students the opportunity to experiment, practice, fail, discover, and learn.

TAKEAWAYS:
1. Beyond Labz simplifies and reduces the cost and expertise needed to provide crucial laboratory experiences and practice for Secondary and Higher Ed students; 2. Attendees will learn how the labs are used for pre- and post-lab experiences, credit recovery and lab make-up, student engagement in class, and meeting NGSS standards; and 3. Basic onboarding and start-up instructions will be provided for drop-in solutions, and instructions for using some of the more sophisticated features will also be described.

SPEAKERS:
Brian Woodfield (Brigham Young University: Provo, UT)

Sponsoring Company: 3D Molecular Designs

Learn how trouble in a yogurt factory exposed CRISPR biology, paving the way for a groundbreaking biotechnology tool. This session explores virus-cell interactions at the boundary of living and nonliving systems.

TAKEAWAYS:
1. To update teachers’ knowledge of bacteria-phage interactions; 2. To demonstrate how teachers can connect this new technology to basic concepts of molecular biology they are already teaching; and 3. To connect a basic biological system to technological innovation.

SPEAKERS:
Christina Bowers (Meridian School: Round Rock, TX)

Sponsoring Company: 3D Molecular Designs

This session introduces CRISPR-Cas9 in the context of DNA, RNA, and protein structure. Functional interactions in the natural system are explained as well as engineered improvements for sequence-specific targeting in the human genome.

TAKEAWAYS:
1. To update teachers’ knowledge of this new gene-editing technology; 2. To demonstrate how teachers can connect this new technology to basic concepts of molecular biology they are already teaching; and 3. To explore the potential and limitations of genome-editing technology applications.

SPEAKERS:
Christina Bowers (Meridian School: Round Rock, TX)

Sponsoring Company: 3D Molecular Designs

Support three-dimensional learning with the hands-on Phospholipid Membrane Transport Kit, exploring the chemical properties of water and the phospholipid bilayer membrane.

TAKEAWAYS:
1. Model how phospholipids spontaneously assemble in water; 2. Identify and simulate the function of the various types of channel proteins involved in membrane transport; and 3. Show how the membrane model can be used over time to add increasingly more advanced topics such as transport of ions or active transport using sodium potassium pumps.

SPEAKERS:
Susan Auld (Sehome High School: Bellingham, WA)

Sponsoring Company: Bio-Rad Laboratories

A COVID-19 outbreak among restaurant customers has researchers puzzled. It's time for your students to analyze DNA samples by electrophoresis and propose evidence-based explanations.

TAKEAWAYS:
1. Walk through a hands-on classroom lab activity to teach about SARS-CoV-2 detection methods; 2. Learn about a case study, based on a publication in 2020, in which researchers analyzed diagnostic data from patrons of a restaurant to learn about how SARS-CoV-2 spreads; and 3. See how students can use classroom lab results to propose evidence-based explanations for how SARS-CoV-2 may have spread in the case study scenario.

SPEAKERS:
Damon Tighe (Bio-Rad Laboratories: Hercules, CA)

Sponsoring Company: 3D Molecular Designs

Let's explore membrane transport and signaling support neuron function. This session covers the relationship between structures and the electrical changes during excitation along with strategies to deepen engagement and understanding.

TAKEAWAYS:
Participants will: 1. deepen their understanding of the molecular mechanisms that support neuron activation and signal propagation during an action potential; 2. become familiar with the specific impacts of neurotransmitters on the pre- and post-synaptic neurons; and 3. use foam models to explore approaches to learning that invite deep questioning, such as via making predictions of the consequences of specific mutations in the sodium potassium pump on neuron activity.

SPEAKERS:
Christina Bowers (Meridian School: Round Rock, TX)

Engage students in a hands-on cellular respiration activity using handouts and pop-beads that help explain the concept.

TAKEAWAYS:
1. Learn the stages of cellular respiration; 2. Discover how to follow glucose through the oxidation steps and track the carbons that are converted to CO2; and 3. Calculate the energy production (ATP) through substrate-level phosphorylation and oxidative phosphorylation.

SPEAKERS:
Deborah Cardenas (Collin College, Wylie Campus: Wylie, TX)